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Request The Product List ofFungal Infection Fungal Infection

Fungal infection, also known as a mycosis, refers to the invasion of a host's tissue by specific types of fungi. Mycoses often start in the lungs following inhalation of fungal spores or on the skin due to localized colonization.

Cat. No. Product Name CAS No. Information
H1232

VT-1161

 		1340593-59-0

VT-1161 is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM; demonstrates >2,000-fold selectivit over human CYP51, weakly inhibits human CYP2C9, CYP2C19, and CYP3A4; exhibits excellent potency against key yeast and dermatophyte strains.
H1231

Voriconazole

 		137234-62-9

Voriconazole is a a triazole antifungal agent that acts as a 14α-demethylase inhibitor; used to treat and prevent invasive fungal infections including aspergillosis andcandidiasis and fungal infections caused by Scedosporium and Fusarium species.

H1230

Terbinafine hydrochloride

 		78628-80-5

Terbinafine hydrochloride is a synthetic antifungal agent that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase; used to treat ringworm, pityriasis versicolor, and fungal nail infections.
H1229

Terbinafine

 		91161-71-6

Terbinafine is a synthetic antifungal agent that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase; used to treat ringworm, pityriasis versicolor, and fungal nail infections.
H1228

SCY-078

 		1207753-03-4

SCY-078 is a novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml); shows actvity in an in vivo neutropenic murine model.
H1226

Posaconazole hydrate

 		1198769-38-8

Posaconazole hydrate is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole.
H1225

Posaconazole

 		171228-49-2

Posaconazole is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole.
H1222

PC945

 		1931946-73-4

PC945(Opelconazole) is a novel broad spectrum antifungal agent that potently inhibits Aspergillus fumigatus sterol 14α-demethylase (CYP51A and CYP51B) with IC50 of 0.23 and 0.22 uM, respectively; shows MIC values 0.032 to >8 ug/ml against 96 clinically isolated A. fumigatus strains, demonstrates activity against itraconazole-susceptible and -resistant A. fumigatus growth with IC50 of 0.0012 to 0.034 ug/ml; PC945 is a broad spectrum of pathogenic fungi with MIC 0.0078 to 2 ug/ml, and exhibits activity in vivo.
H1220

Nystatin

 		1400-61-9

Nystatin is a polyene antifungal antibiotic that works by disrupting the cell membrane of the fungal cells.
H1218

Micafungin

 		235114-32-6

Micafungin is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.

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