| Cat. No. |
Product Name |
CAS No. |
Information |
| H9581 |
Onradivir
|
2200336-20-3 |
Onradivir is a significantly better anti-influenza virus agent extracted. |
| H8989 |
CBS1117
|
959245-08-0 |
CBS1117 is a novel fusion inhibitor, CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A viruses, A/Puerto Rico/8/34 (H1N1); CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process. |
| H6458 |
KIN-1148
|
1428729-56-9 |
A small-molecule IRF3 agonist that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters; functions as an influenza vaccine adjuvant by modulating the antiviral immune response. |
| H8385 |
Neuraminidase-IN-1
|
2379438-80-7 |
Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus and good inhibitory effect on the A/WSN/33 H1N1 virus strains. |
| H1448 |
Zanamivir
|
139110-80-8 |
Zanamivir is a hihly potent, broad-spetrum influenza viral neuraminidase (NA) inhibitor with IC50 of 0.95 nM and 2.7 nM for influenza A and B, respectively; inhibits plaque formation by laboratory-passaged strains of influenza A and B viruses,IC50 ranging from 0.005 to 0.014 uM; interacts with a group of amino acids in the active site of neuraminidase, which are conserved in all influenza A and B strains. Zanamivir blocks the action of neuraminidase, which prevents the cleavage of sialic acid on the cell receptors, thus preventing release and spread of the newly formed virions. |
| H1447 |
Triazavirin
|
928659-17-0 |
Triazavirin (Riamilovir sodium dihydrate) is a broad-spectrum antiviral agent targeting influenza viruses, lassa virus, TBEV and Ebola virus; suppresses the replication of influenza virus in cell culture and in chicken chorioallantoic membranes, and protects mice from death caused by type A and B influenza viruses. |
| H1446 |
T-1105
|
55321-99-8 |
T-1105 is a broad-spectrum antiviral inhibitor that demonstrates good activity for various RNA viruses, including influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), FMDV, and ZIKV; inhibits ZIKV replication with EC50 of 35 uM in a virus yield reduction assay. |
| H1445 |
S119-8
|
443639-96-1 |
S119-8 (Influenza inhibitor S119-8) is a novel broad spectrum inhibitor of influenza virus replication (IC50=1.43 nM) by targeting the viral Nucleoprotein (NP), with no detectable cytotoxicity (CC50>50 uM); also shows activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus, does not inhibit a non-influenza virus, VSV; exhibits synergistic combined with in vitro viral inhibition assays. |
| H1444 |
RO-7
|
1370241-45-4 |
RO-7 is a novel small molecule, broad-spectrum inhibitor of influenza acidic polymerase (PA) protein endonuclease activity with EC50 of 3.2-16 nM in MDCK cells; inhibits transcription and genome replication steps in the influenza virus cycle, demonstrates activity against NAI-resistant and -susceptible seasonal influenza A and B viruses; also shows activity against avian-origin A(H5N1), A(H7N9), and A(H9N2) influenza viruses. |
| H1443 |
R 125489
|
203120-17-6 |
R 125489 (Laninamivir) is a potent influenza neuraminidase (NA) inhibitor, inhibits the NA activities of various type A and B influenza viruses, including subtypes N1 to N9 and oseltamivir-resistant viruses. |
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