Severe acute respiratory syndrome (SARS) is an acute respiratory infectious disease caused by SARS coronavirus (SARS CoV). The World Health Organization (who) named it as SARS. The disease is a respiratory infectious disease, the main mode of transmission is close to the spread of droplets or contact with respiratory secretions of patients.
Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
H9433 |
Enpatoran hydrochloride |
2101945-93-9 | Enpatoran (M5049) hydrochloride is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively; Enpatoran hydrochloride is inactive against TLR3, TLR4 and TLR9. Enpatoran hydrochloride can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran hydrochloride exhibits excellent pharmacokinetic properties in vivo. Enpatoran hydrochloride can be used for both innate and adaptive autoimmunity blocking research. |
H9366 |
Zavegepant hydrochloride |
1414976-20-7 | Zavegepant is a potent human CGRP antagonist with Ki of 22.7 pM. |
H9365 |
Zavegepant |
1337918-83-8 | Zavegepant is a potent human CGRP antagonist with Ki of 22.7 pM. |
H9280 |
Naproxcinod |
163133-43-5 | Naproxcinod, a Cyclooxygenase-Inhibiting Nitric Oxide (NO)-Donating (CINOD) naproxen, is a non-steroidal anti-inflammatory product candidate originally. |
H9278 |
WP 1122 |
155196-44-4 | WP 1122 is a potent coronavirus spike glycoprotein modulators. |
H9275 |
Brilacidin |
1224095-98-0 | Brilacidin is an investigational new drug (IND), is a polymer-based antibiotic currently in human clinical trials, and represents a new class of antibiotics called host defense protein mimetics, or HDP-mimetics, which are non-peptide synthetic small molecules modeled after host defense peptides (HDPs). |
H9274 |
PF-07304814 |
2468015-78-1 | Lufotrelvir(PF07304814) is a novel phosphate prodrug for PF-00835231,PF-07304814 rapidly undergoes in vivo conversion to the active metabolite PF-00835231. The phosphate prodrug is weakly acidic, with pKas of 1 and 6.4, and a predicted LogD7.4 of -3.7 |
H9271 |
AT-527 |
2241337-84-6 | AT-527 is a novel modified guanosine nucleotide prodrug inhibitor of the hepatitis C virus (HCV) NS5B polymerase, with increased in vitro antiviral activity compared to sofosbuvir and a highly differentiated favorable preclinical profile compared to other anti-HCV nucleoside/nucleotide analogs. |
H9217 |
AMY-101 |
1427001-89-5 | AMY-101 is a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs); AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation. |
H9141 |
Nicotinamide riboside |
1341-23-7 | Nicotinamide riboside is an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease. |
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