Welcome to Hmobio!Global leader in active molecules.
Find Your Distributors

Select Your Country or Region

 $ USD

For research purposes only. Not for human experiments
You are here:Home-PROTACs-PROTAC Linkers

Request The Product List ofPROTAC Linkers PROTAC Linkers

The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.

Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.

Cat. No. Product Name CAS No. Information
H8999

ABM-14

 		1973408-76-2

ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC. ABM-14 binds to a ligand for VHL via linker to form ARCC-4 (HY-130492) to degrade AR.
H8914

m-PEG9-phosphonic acid ethyl ester

m-PEG9-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
H8913

TCO-PEG8-amine

 		2353409-92-2

TCO-PEG8-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
H8912

m-PEG6-2-methylacrylate

 		90784-86-4

m-PEG6-2-methylacrylate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
H8911

4-Maleimidobutyric acid

 		57078-98-5

4-Maleimidobutyric acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
H8910

m-PEG5-Boc

 		874208-93-2

m-PEG5-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
H8909

m-PEG2-phosphonic acid

 		96962-41-3

m-PEG2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
H8908

NH-bis-PEG5

 		63721-06-2

NH-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
H8907

Amino-PEG4-CH2COOH

 		195071-49-9

Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
H8906

Thiol-PEG-CH2COOH (MW 3400)

Thiol-PEG-CH2COOH (MW 3400) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:
© Copyright 2020 HmoBio. All Rights Reserved. Products are only for research use
沪ICP备2020027822号-1