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You are here:Home-Inhibitors & Agonists-Immunology/Inflammation-Scavenger Receptor

Request The Product List ofScavenger Receptor Scavenger Receptor

Cat. No. Product Name CAS No. Information
H4069

ML 279

 		1604821-55-7

ML279 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 17 nM; stabilizes the interaction of HDL particles with SR-BI, and is non-toxic, plasma stable, and has improved solubility over alternative probe ML278.
H4068

ML 278

 		1604821-43-3

ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM; a plasma-stable, noncytotoxic probe that exhibits moderate metabolic stability, thus displaying improved properties for in vitro and in vivo studies; increases the binding of HDL to SR-BI.
H4067

ITX-5061 hydrochloride

 		1252679-52-9

ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels; inhibits SR-BI-dependent uptake of HDL-CE in transfected cells, decreases the fractional catabolic rate of HDL-CE and reduced its hepatic uptake in mice; inhibits HCVcc and HCVpp infection of primary human hepatocytes and/or human hepatoma cell lines and has minimal effects on HCV RNA replication.
H4066

ITX-5061

 		848144-15-0

ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels; inhibits SR-BI-dependent uptake of HDL-CE in transfected cells, decreases the fractional catabolic rate of HDL-CE and reduced its hepatic uptake in mice; inhibits HCVcc and HCVpp infection of primary human hepatocytes and/or human hepatoma cell lines and has minimal effects on HCV RNA replication.
H4065

BLT-1

 		321673-30-7

BLT-1 is an irreversible Scavenger receptor class B member I (SR-BI) inhibitor that blocks SR-BI-mediated selective lipid uptake and bidirectional cholesterol flux with an IC50 of 50 nM; significantly inhibits baicalin-induced cholesterol efflux in THP-1 macrophages.

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