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Valproic acid (VPA;2-Propylpentanoic Acid) Catalog No. H2634

Valproic acid

CAS No.: 99-66-1

Valproic acid(VPA;2-Propylpentanoic Acid)

Catalog No.: H2634

A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2

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500 mg USD 35 In stock
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Purity & Documentation Purity: 98% (HPLC) Select Batch:

Biological Activity

A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2; induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from AML patients; reduces tumor growth and metastasis formation in animal model.

References

1. Kr?mer OH, et al. EMBO J. 2003 Jul 1;22(13):3411-20.

2. G?ttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.

3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.

Clinical Information

Migraine
Approved

Physicochemical Properties

M.Wt 144.2114
Formula C8H16O2
CAS No. 99-66-1
Storage
Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 3 Month
Shipping
Solubility

10 mM in H2O
Chemical Name/SMILES Pentanoic acid, 2-propyl-

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